Euglobulin lysis time
Euglobulin lysis time (ELT) is a blood test that looks at how fast clots break down in the blood.
Euglobulin clot lysis; Fibrinolysis/euglobulin lysis; ELT
How the Test is Performed
How to Prepare for the Test
How the Test will Feel
Why the Test is Performed
This is one of the best tests to tell the difference between primary fibrinolysis and disseminated intravascular coagulation.
The test can also be used to monitor patients who are on streptokinase or urokinase therapy for acute MI (heart attack).
A normal value will range from 90 minutes to 6 hours. Euglobulin clot lysis is normally complete within 2 to 4 hours.
Note: Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.
What Abnormal Results Mean
A longer-than-normal ELT time may be due to:
A shorter-than-normal ELT time may be due to:
The test may also be done to diagnose or rule out:
- Excessive bleeding
- Fainting or feeling light-headed
- Hematoma (blood accumulating under the skin)
- Infection (a slight risk any time the skin is broken)
Lijnen HR, Collen D. Molecular and cellular basis of fibrinolysis. In: Hoffman R, Benz EJ Jr., Shattil SJ, et al, eds. Hoffman Hematology: Basic Principles and Practice. 5th ed. Philadelphia, PA: Churchill Livingstone Elsevier; 2008:chap 119.
Schafer A. Hemorrhagic disorders: Disseminated intravascular coagulation, liver failure, and vitamin K deficiency. In: Goldman L, Ausiello D, eds. Goldman's Cecil Medicine. 23rd ed. Philadelphia, PA: Saunders Elsevier; 2007:chap 181.
Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by A.D.A.M. Health Solutions, Ebix, Inc., Editorial Team: David Zieve, MD, MHA, Bethanne Black, Stephanie Slon, and Nissi Wang.
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